What is Cannabinoid Hyperemesis Syndrome CHS?

GARD uses data collected from Orphanet,  Online Mendelian Inheritance in Man (OMIM) , and Mondo Disease Ontology  to interpret and provide information on rare diseases. This includes names, synonyms, genes, symptom frequency, population estimates and more. Splanchnic vasodilation – THC alters blood flow, potentially contributing to nausea and abdominal pain. Pancreatitis – Inflammation of the pancreas causing severe abdominal pain and nausea. Gallbladder Disease – Biliary dysfunction causing nausea and vomiting. This page provides a comprehensive, evidence-based perspective on CHS, distinguishing it from other conditions and outlining a more effective, patient-centered Substance abuse approach to management.

Treatment reference

Gastroparesis – Delayed stomach emptying causing chronic nausea and bloating. That’s why our programs are founded and staffed by people in recovery – people who truly understand. As CHS is a new diagnosis, the manufacturers of these drugs did not design them for treating CHS, but a doctor may opt to prescribe them for this use. Another doctor reported using a combination of injectable lorazepam and promethazine, another antinausea medication. The symptoms typically last a few weeks, though the throwing up should ease up in a day or two.

chs syndrome symptoms

What is the treatment for cannabinoid hyperemesis treatment?

Some have suggested that high doses might cause the anti-emetic effects to flip into a pro-emetic syndrome. These cases highlight the importance of finding better ways to distinguish CHS from other conditions that manifest in similar ways. Soon Facebook groups dedicated to CHS started to appear as well, with thousands of people who claimed they had these same symptoms. So far, the only known way to completely resolve symptoms of CHS is to stop all cannabinoid use. Now, 20 years later, cases of CHS have risen dramatically in areas with legal cannabis access, and researchers have learned a lot more about what CHS is, who is likely to get it, and how to get it to stop.

What role do hot showers play in managing CHS symptoms?

People living with rare diseases often face challenges such as delayed diagnosis, limited treatment options, and difficulty accessing knowledgeable providers. Building a care team that understands your needs can make a significant difference in your quality of life. The most effective treatment for CHS is https://ecosoberhouse.com/ the complete cessation of cannabis use. During acute episodes, supportive care includes intravenous fluids, anti-nausea medications, pain management, and topical capsaicin cream.

Treatments for Alcohol Use Disorder

Cannabis cessation is the most effective treatment for CHS, with nearly all patients experiencing symptom resolution within 10 days of stopping use. Long-term recovery requires complete abstinence to prevent relapse. A 2019 article reported on thedeaths of three patients who experienced CHS; two of these deaths were directly caused by CHS-related dehydration, which caused low blood sugar and electrolyte abnormalities. These chemical disturbances in the body caused cardiac arrest in one patient and kidney failure in the other patient, leading to their deaths. The only definitive cure for CHS, for now, is tostop using marijuana. Some people may try to restart marijuana use after the severe symptoms subside, but CHS can return.

chs syndrome symptoms

How to Tell If It’s Cannabis Hyperemesis Syndrome (CHS)?

The direct effects of cannabinoids include the activation of cannabinoid receptors on the surface of GI cells, which can influence the release of neurotransmitters and hormones that regulate GI function. For most users, cannabis remains a safe and beneficial therapeutic option. However, being aware of CHS and its symptoms allows users to take proactive steps if they experience any adverse effects. If you or someone you know experiences recurrent nausea and vomiting with regular cannabis use, consulting a healthcare provider and considering a reduction or cessation of cannabis use might be beneficial. Responsible and informed consumption is key to enjoying the many benefits that cannabis has to offer. Seeing multiple specialists is important for people with rare diseases because these conditions often affect many parts of the body and require care from doctors with different expertise.

What are the treatment options for Chediak-Higashi syndrome?

These infections can be painful and may require antibiotic or antifungal treatment. During this phase, the main symptoms are often early morning nausea and belly (abdominal) pain. Some people use more marijuana because they think it will help stop the nausea.

  • For those experiencing symptoms, seeking prompt medical care is essential, particularly during the hyperemetic phase, when complications are more likely to occur.
  • First outlined in 2004, CHS remains a condition of uncertain etiology.
  • Researchers believe it happens due to overstimulation of the body’s endocannabinoid system (ECS).
  • Photophobia, or sensitivity to light, affects about 60% of CHS patients.
  • If you need help quitting, ask your doctor whether a drug rehabilitation program is a good fit for you.

Although there’s no official reason for why this provides relief for CHS patients, scientists believe that warm temperatures correct the cannabis-induced disequilibrium at the thermoregulatory centers. Heat/hot showers also activates TRPV1 which helps with inhibiting pain signals, resulting in analgesic and antiemetic effects. Understanding the underlying genetic cause is crucial for managing the condition and providing appropriate care. If you or a loved one has what is chs weed been diagnosed with Chediak-Higashi Syndrome, it’s important to work closely with healthcare providers to develop a comprehensive treatment plan. If a diagnosis, care management, or treatment plan remains unclear despite extensive efforts by your PCP and specialists, it may be time to find a rare disease expert for your disease, if available. A rare disease expert is a medical provider that has knowledge or training on specific rare disease(s), but there may only be a few experts in your state, region, or country.

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